Whole-genome bisulfite sequencing (WGBS) was performed on oocytes collected from 16 twin ewe pairs (8 methionine-treated and 8 controls). These ewes were later bred to control rams, and embryos were f
Genome wide DNA methylation profiling of 32 hereditary leiomyomatosis and renal cell cancer patient-derived samples. The Illumina Infinium 850k Human DNA methylation Beadchip was used to obtain DNA me
The respective role of genetic and epigenetic heterogeneity in the functional diversity of cells that compose human malignancies remains poorly understood. This question is addressed in chronic myelom