气相色谱—质谱联用仪校准装置

本计量标准由三种国家二级标准物质、铂电阻温度计、气相色谱仪检定装置等部分组成，

1、八氟萘-异辛烷溶液标准物质，100pg/μl。该标准物质用于测试GC-MS负CI和EI源灵敏度，使用微量注射器进1.0μl标准物质，提取m/z=272离子，再现质量色谱图，根据公式（1）计算S/N。

S/N=H 272 /H噪声 （1）

式中：

H272：提取离子（m/z）的峰高

H噪声：基线噪声。

2、苯甲酮-异辛烷溶液标准物质，10.0ng/？L。该标准物质用于测试GC-MS正CI源灵敏度，使用微量注射器进1.0μl标准物质，提取m/z=183离子，再现质量色谱图，根据公式（1）计算S/N。

3、六氯苯-异辛烷溶液标准物质，10.0ng/？L。该标准物质用于测试GC-MS测量重复性，使用微量注射器进1.0μl标准物质，连续测量六次，提取六氯苯特征离子m/z=284，再现质量色谱图，按质量色谱峰进行面积积分，根据公式（2）计算RSD：

×100%（2）

式中：

RSD-相对标准偏差（%）；

xi-六氯苯第i 次测量峰面积；

-六氯苯6次测量峰面积算术平均值；

i-测量序号。

This metrological standard comprises three national secondary reference materials, a platinum resistance thermometer, a gas chromatograph verification device, and other components.
1. Octafluoronaphthalene-isooctane solution reference material, 100 pg/μL. This reference material is used to test the sensitivity of GC-MS negative CI and EI sources. Inject 1.0 μL of the reference material with a microsyringe, extract the ion at m/z = 272 to generate the mass chromatogram, and calculate the signal-to-noise ratio (S/N) according to Equation (1):
$S/N = H_{272} / H_{ ext{noise}}$ (1)
Where:
$H_{272}$: Peak height of the extracted ion (m/z)
$H_{ ext{noise}}$: Baseline noise.
2. Benzophenone-isooctane solution reference material, 10.0 ng/μL. This reference material is used to test the sensitivity of GC-MS positive CI source. Inject 1.0 μL of the reference material with a microsyringe, extract the ion at m/z = 183 to generate the mass chromatogram, and calculate the S/N ratio according to Equation (1).
3. Hexachlorobenzene-isooctane solution reference material, 10.0 ng/μL. This reference material is used to test the measurement repeatability of GC-MS. Inject 1.0 μL of the reference material with a microsyringe, perform six consecutive measurements, extract the characteristic ion at m/z = 284 of hexachlorobenzene to generate the mass chromatogram, conduct area integration based on the mass chromatographic peaks, and calculate the relative standard deviation (RSD) according to Equation (2):
$ imes100\%$ (2)
Where:
$ ext{RSD}$: Relative standard deviation (%)
$x_i$: Peak area of the i-th measurement of hexachlorobenzene
$ar{x}$: Arithmetic mean of the peak areas of six measurements of hexachlorobenzene
$i$: Measurement serial number.