Here, we revealed that an intestinal T cell subset, derived from already differentiated TH17 cells, induces the spontaneous transformation of the healthy epithelium. This subset produces a large panel
Donor OTUD1 deficiency significanltly ameliorates the severity of aGVHD mice. We used single cell RNA sequencing (scRNA-seq) to analyze the immune cells in aGVHD mice transferred wild type or OTUD1-de