Gene expression changes characterization in whole body Drosophila melanogaster mated females as a function of chronological age and Smurf status Overall design: Comparative gene expression profiling a
Aging is an intricate biological event that occurs in both vertebrates and invertebrates. During the aging process, the brain, a vulnerable organ, undergoes structural and functional alterations, resu
Abstract Dietary restriction (DR) is a well-established intervention to extend lifespan across taxa. Recent studies suggest that DR-driven lifespan extension can be cost-free, calling i
Purpose: The goal of this study was to identify differential splicing events in the Drosophila eye during aging. Overall design: Method: RNA extracted from dissected eye tissue of flies aged 10 and 40