官方服务:
资源简介:
RNA off-target assessment of Td-BEs.
应用场景:
创建时间:
2022-04-23
相关数据集
Harnessing Self-Labeling Enzymes for Selective and Concurrent A-to-I and C-to-U RNA Base Editing
The SNAP-ADAR tool enables precise and efficient A-to-I RNA editing in a guideRNA-dependent manner by applying the self-labeling SNAP-tag enzyme to generate RNA-guided editases in cell culture. Here
NIAID Data Ecosystem80
Negative autoregulation mitigates collateral RNase activity of repeat-targeting CRISPR-Cas13d in mammalian cells
Cas13 is a unique family of CRISPR endonucleases exhibiting programmable binding and cleavage of RNAs and is a strong candidate for eukaryotic RNA knockdown in the laboratory and the clinic. However,
NIAID Data Ecosystem40
Engineered APOBEC3A deaminase variants for highly accurate and efficient cytosine base editing
RNA off-target assessment of CBE variants.
NIAID Data Ecosystem50
Comprehensive evaluation of adenine base editors induced mutations at genomic and transcriptional level [WGS]
Adenine base editors (ABEs) with wide CRISPR compatibility and high activity improves the editing efficiency and arouses the off-target challenges as well. Here, we carried out a comprehensive evaluat
NIAID Data Ecosystem40



