IL-6 signaling in CD8 T cells promotes resistance to anti-PD-L1 immunotherapy

NIAID Data Ecosystem2026-03-14 收录

癌细胞耐药性

IL-6信号通路

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE199048 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2023-02-07

Supplementary Material for: Transcription factor Sox9 exacerbates kidney injury through inhibition of microRNA-96-5p and activation of the Trib3/IL-6 axis

肾损伤

IL-6信号通路

Introduction: Our study investigated the possible mechanisms of the role of the transcription factor Sox9 in the development and progression of kidney injury through regulation of the miR-96-5p/Trib3/

DataCite Commons2023-10-18 更新90

Identificatinon of differentially expressed genes in Docetaxel-resistant cell lines PC3 and DU145 after combination treatment with RU486 and docetaxel

癌细胞耐药性

药物组合治疗评估

Upregulation of the glucocorticoid receptor (GR) has been identified as a possible bypass mechanism in CRPC. Recently, it has been demonstrated that the combination of docetaxel with mifepristone (D+M

NIAID Data Ecosystem00

ATAC-seq in cadmium resistant breast cancer MDA-MB-231 cells

癌细胞耐药性

ATAC-seq染色质可及性

In this study, we compared ATAC-seq of cadmium resistant MDA-MB-231 cells vs untreated controls. Overall design: In this study, we compared ATAC-seq for MDA-MB-231 cells treated long term with 10uM ca

NIAID Data Ecosystem00

Transcriptional adaptation and enhancer rewiring promote metabolic resistance in BRAFmutated multiple myeloma (bulkRNA-seq)

癌细胞耐药性

转录组学治疗

Purpose: We examined how transcriptional state changes relate to clonal selection as BRAF inhibitor resistance develops in BRAF-mutated myeloma. Methods: To this end we generated three single-cell clo

NIAID Data Ecosystem40

Genomic DNA sequencing of human therapy resistant rhabdomyosarcoma

肿瘤基因组学

癌细胞耐药性

Xenograft models that were sensitive or developed resistance to Olaparib and temozolomide (OT) combination therapy.

NIAID Data Ecosystem00