VRK1 and VRK2A sensitivity and IC50 values of serine-threonine kinase inhibitors.

The IC50 values were calculated in the presence of 5 µM ATP. The individual points are the average from three experiments. The linear regression and the standard deviation were calculated with the SPSS program for VRK1 (Fig. S3) and VRK2A (Fig. S4). All values are µM. No inhibition is lack of effect at 100 µM.