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资源简介：
CO-culture of Microglia and Neurons
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创建时间：
2024-11-21
相关数据集
Moderate intrinsic phenotypic alterations in C9orf72 ALS/FTD iPSC-microglia despite the presence of C9orf72 pathological features
To differentiate, characterize and examine intrinsic phenotypes of C9orf72 ALS/FTD patient-derived induced pluripotent stem cells into microglia (iPSC-MG). Moderate molecular and functional difference
NIAID Data Ecosystem80
Directly converted astrocytes retain the ageing features of the donor fibroblasts and elucidate the astrocytic contribution to human CNS health and disease.
To interrogate the transcriptional features of fibroblast-derived iAstrocytes in relation to their ageing phenotype, we compared transcriptomic data from iAstrocytes obtained from old and young donors
DataCite Commons2021-01-25 更新60
Data used to generate S9A and S9C–S9D Fig.
TDP-43 pathology is a hallmark of fatal neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and limbic-predominant age-related TDP-43-encephalopa
Figshare2026-03-24 更新30
Mitochondrion to endoplasmic reticulum apposition length in zebrafish embryo spinal progenitors is unchanged in response to perturbations associated with Alzheimer’s disease
Mutations in the human genes PRESENILIN1 (PSEN1), PRESENILIN2 (PSEN2) and AMYLOID BETA A4 PRECURSOR PROTEIN (APP) have been identified in familial Alzheimer’s disease (AD). The length of mitochondrion
NIAID Data Ecosystem60
Data used to generate Fig 3B–C.
TDP-43 pathology is a hallmark of fatal neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and limbic-predominant age-related TDP-43-encephalopa
Figshare2026-03-24 更新60
