INSULIN RESISTANCE IS THE MOST PRESSING PATHOLOGY OF OUR CENTURY

Insulin resistance is the loss of sensitivity of the body's cells to the hormone insulin. This is a pathological condition, Insulin (Latin insula - islet) is a protein hormone of animal and human origin. It is produced in the islets of Langerhans of the pancreas. It was first isolated by Canadian scientists F. Banting and Ch. Best (1921-22). Mol. m. 6000. The insulin molecule is composed of two polypeptide chains connected by disulfide bonds and consists of 51 amino acid residues. The sequential arrangement of amino acid residues in insulin was determined by the English biochemist F. Sanger (1945-56). This made it possible to synthesize insulin chemically. Insulin was synthesized by chemical and genetic engineering. Insulin is the first protein whose amino acid sequence was determined.