Crystal structure of Keap1 Kelch domain (residues 322-609) in complex with 6k
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Crystal structure of Keap1 Kelch domain (residues 322-609) in complex with 6k Descriptor: Kelch-like ECH-associated protein 1, N-[4-[(2-azanyl-2-oxidanylidene-ethyl)-[4-[(2-azanyl-2-oxidanylidene-ethyl)-(4-methoxyphenyl)sulfonyl-amino]naphthalen-1-yl]sulfamoyl]phenyl]-3-(4-ethylpiperazin-1-yl)propanamide Authors: Xu, K. Deposit date: 2022-04-24 Release date: 2022-07-06 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystallography-Guided Optimizations of the Keap1-Nrf2 Inhibitors on the Solvent Exposed Region: From Symmetric to Asymmetric Naphthalenesulfonamides. J.Med.Chem., 65, 2022
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2022-04-24
