'冰毒成瘾猴模型'的相关数据

该研究工作建立了从神经元到动物行为水平衡量超声神经调控效应的研究范式，利用双光子活体钙成像技术和阵发性运动障碍模型小鼠，发现低强度超声对小脑皮层神经活动具有直接兴奋作用，提示了经颅超声作为一种新型的非侵入式神经调控技术，具有潜在的广泛应用。This study establishes a research paradigm for quantifying the effects of ultrasonic neuromodulation across scales ranging from neuronal activity to animal behavior. By employing two-photon in vivo calcium imaging and mouse models of paroxysmal dyskinesia, the study found that low-intensity ultrasound exerts a direct excitatory effect on the neural activity of the cerebellar cortex, suggesting that transcranial ultrasound, as a novel non-invasive neuromodulation technology, has broad potential applications.