Relative reactivity of nucleosides in the central loop of Domain V of 23S rRNA, when a CAM dimer (I) binds to <i>E</i>. <i>coli</i> ribosomes (R) in the initial (RI) and the final (R*I) binding sites^a.

aRelative reactivity of nucleosides denotes the ratio between the normalized intensity of a band of interest and the normalized intensity of the homologous band in the control lane (R) (see also S2 Fig). bSignificantly different in relation to R (P<0.05). cSignificantly different in relation to RI (P<0.05). Relative reactivity of nucleosides in the central loop of Domain V of 23S rRNA, when a CAM dimer (I) binds to E. coli ribosomes (R) in the initial (RI) and the final (R*I) binding sitesa.