Human PDE9 in complex with selective inhibitor
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Human PDE9 in complex with selective inhibitor Descriptor: 6-[(3S,4S)-1-benzyl-4-methylpyrrolidin-3-yl]-1-(1-methylethyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, MAGNESIUM ION, ... Authors: Liu, S. Deposit date: 2009-09-11 Release date: 2009-12-01 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Identification of a Brain Penetrant PDE9A Inhibitor Utilizing Prospective Design and Chemical Enablement as a Rapid Lead Optimization Strategy. J.Med.Chem., 52, 2009
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2009-09-11
