Kinesin spindle protein Eg5 in complex with ATP-competitive inhibitor PVZB1194 Descriptor: 3'-fluoro-4'-(trifluoromethyl)biphenyl-4-sulfonamide, Kinesin-like protein KIF11 Authors: Yokoyama, H, Katoh,
So far, relatively few small molecules have been reported to promote tubulin degradation. Our previous studies have found that compound 2, a noncovalent colchicine-site ligand, was capable of promotin
Hypoxia inducible factors (HIFs) are transcription factors belonging to the basic helix−loop−helix PER-ARNT-SIM (bHLH-PAS) protein family with a role in sensing oxygen levels in the cell. Under hypoxi
HUMAN GAR TRANSFORMYLASE IN COMPLEX WITH GAR AND (S)-2-({4-[3-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-6-YL)-PROPYL]-THIOPHENE-2-CARBONYL}-AMINO)-PENTANEDIOIC ACID Descriptor: (S)-2-({4-[
