KIF20A inhibition affects the divisions of embryos.

(A) Schematic diagram of cleavage of early embryos in different groups. The black arrow indicated a 4-cell embryo in control group.(B) Effect of KIF20A inhibition on cleavage ability of zygotes. The embryonic development rate has dropped after KIF20A activity inhibition. Almost all of the embryos cleaved normally in the control groups, while the cleavage of embryos was blocked in treatment groups, especially in the 50 µM groups. * significant difference (p<0.05).