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Retrotransposons and the global shutdown of homeostatic innate immunity in the tumor cells by oncolytic parvovirus H-1PV

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NIAID Data Ecosystem2026-03-12 收录
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RNAseq-based comparison of H-1PV infected vs. non-infected cells revealed global suppression of antiviral innate immunity in the PDAC cells (AsPC1, MiaPaca2 and T3M4 taken at 48hpi) and global stimulation – in the healthy donor PBMCs (taken at 24hpi). Overall design: total RNA profile +/- infection with H-1PV of 3 pancreatic cancer cell lines (48h) and healthy donor PBMCs (24h)

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2021-07-03
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