Major histocompatibility complex (MHC) genetics dictate adaptive cellular immune responses, making robust MHC genotypin g methods essential for studies of infectious disease, vaccine development and t
Additional file 4: Supplementary Table S2. KIRCLE-inferred KIR allele genotypes in UK Biobank. Number of copies of each of 535 KIR coding alleles in 49,694 UK Biobank samples. Note that UK Biobank ID
The killer-cell immunoglobulin-like receptor (KIR) proteins evolve to fight viruses and mediate the body’s reaction to pregnancy. These roles provide selection pressure for variation at both the struc
PING genotype determination performance for the European reference cohort, a synthetic KIR dataset, and the Khoesan reference cohort for each considered KIR gene.
