Hepatic gene expression analysis from rats with chronic sleep restriction

We report the change in gene expression in rat liver post chronic sleep restriction. Rats were sleep restricted by for 5 days by forced activity protocol. We found changes in genes related to NAD metabolism (Nampt), TCA cycle (Acly) and methionine metabolism (Msrb2 and Mtr) Overall design: Examination of differential expression from liver of rats undergoing forced activity plus sleep restriction and force activity only