官方服务:
资源简介:
Human Colorectal Cancer (AA-A01I-01A-12)
应用场景:
创建时间:
2014-12-31
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Abstract
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Whole genome copy number profiles of FFPE samples from patients with metasatic colorectal cancer (mCRC)
Metastatic colorectal cancer (mCRC) is associated with multiple somatic copy number alterations (SCNAs). We analyzed SCNAs to estimate overall survival (OS) and progression free suvival (PFS) for mCRC
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To address the need for understanding ITH in CRC comprehensively and accurately, we used targeted deep next-generation sequencing of 799 genes to characterize the genetic profiles of four CRCs, followed by validation with ultra-high-depth amplicon sequencing. We also performed NanoString gene expression profiling and NanoString cancer copy number analysis.. Multi-region ultra-deep sequencing reveals early inter-mixing and variable levels of intratumoral heterogeneity in colorectal cancer
Background: Intratumor heterogeneity (ITH) contributes to cancer progression and chemoresistance. We sought to comprehensively describe ITH of somatic mutations, copy number and transcriptomic alterat
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Supplemental material, sj-xlsx-2-jbm-10.1177_03936155221095574 for Correlation of KMT2 family mutations with molecular characteristics and prognosis in colorectal cancer by Cun Liao, Wei Huang, Mingli
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Genomic landscape of Chordoid Glioma
Chordoid glioma (ChG) is a characteristic, slow growing and well-circumscribed diencephalic tumor, whose mutational landscape is unknown. We analyzed primary chordoid glioma samples by whole exome seq
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