We performed single nucleus RNA sequencing (snRNA-seq) and assay for transposase-accessible chromatin with sequencing (snATAC-seq) to map the epigenetic and gene expression signatures of human kidney

NIAID Data Ecosystem30

Gene expression profiling of human iPSC kidney organoid-derived proximal tubules

类器官分化

近端小管转录组学

The kidney organoid differentiation protocol takes induced pluripotent stem cells through to kidney organoid via directed differentiation in approximately 25 days. The cells are grown in a monolayer i

NIAID Data Ecosystem10

Data_Sheet_1_Distinct Mitochondrial Remodeling During Mesoderm Differentiation in a Human-Based Stem Cell Model.PDF

干细胞代谢

中内胚层分化

Given the considerable interest in using stem cells for modeling and treating disease, it is essential to understand what regulates self-renewal and differentiation. Remodeling of mitochondria and met

NIAID Data Ecosystem30

SB431452 affects extracellular matrix during induction of hiPSC-derived gastric organoid with muscularis mucosa

类器官分化

TGF-β信号通路调控

We report TGFβ signaling is involved in muscularis mucosa differentiation of hiPSC-derived gastric organoids. Comparison of RNA expression of hiPSC-derived gastric organoid treated with or without SB4

NIAID Data Ecosystem20

iPSC-Derived Kidney Organoid Differentiation

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