Analysis of T-cells lacking the proprotein convertase furin. Proprotein convertases promote the proteolytic maturation of proproteins. Furin is induced in activated T-cells. Results provide insight in
The recently developed transcription, epitopes, and chromatin accessibility by sequencing (TEA-seq) and similar DOGMA-seq single-cell trimodal omics assays provide unprecedented opportunities for unde
Additional file 5: Supplementary Table 4. Clusters of upregulation 24 hours after TCR activation in Th17 polarizing conditions in CD4+ T cells. Each column represents one cluster. The first row in eac