Genetic linkage map of serotype D (B-3501 x B-3502). Cryptococcus deneoformans strain:B3501 X B3502

Marra et al. at Duke University constructed a Cryptococcus neoformans var. neoformans serotype D genetic linkage map using 94 progeny from a cross between strains B-3501 and B-3502. They identified twenty linkage groups (LGs) based on segregation analysis of 301 polymorphic markers consisting of 228 restriction site polymorphisms, 63 microsatellites, two indels, and eight mating-type (MAT)-associated markers. Marra et al. assigned the LGs to specific chromosomes. All chromosomes except chromosome 10 are represented by at least one LG; however, two of 12 ungrouped markers map to chromosome 10. Marra et al. found evidence for possible reciprocal translocations involving chromosomes 8, 9, and 12.