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One-Pot Homolytic Aromatic Substitutions/HWE Olefinations under Microwave Conditions for the Formation of a Small Oxindole Library

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NIAID Data Ecosystem2026-03-06 收录
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An efficient one-pot sequence comprising a homolytic aromatic substitution followed by an ionic Horner−Wadsworth−Emmons olefination for the preparation of a small library of α,β-unsaturated oxindoles is presented. Microwave-induced heating is used to conduct these reactions. The homolytic aromatic substitution is mediated by the persistent radical effect.

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2016-05-06
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