PAS

In this project, we focused on the development of an annotated gene-disease-code database, which is accessible through an online, cross-platform and user-friendly application, i.e. PROMIS-APP-SUITE-Gene-Disease-Code. However, our scope is limited to the integration of ICD-9 and ICD-10 codes with the list of genes approved by the American College of Medical Genetics and Genomics. The results include over 17 000 diseases and 4000 ICD codes, and over 11 000 gene-disease-code combinations. Database URL https://promis.rutgers.edu/pas/.本研究聚焦于开发一款注释型基因-疾病-编码数据库，该数据库可通过一款在线、跨平台且易用的应用程序——PROMIS-APP-SUITE-Gene-Disease-Code——进行访问。不过，本研究的覆盖范围仅限将国际疾病分类第9版（ICD-9）、国际疾病分类第10版（ICD-10）编码，与美国医学遗传学与基因组学学会（American College of Medical Genetics and Genomics）批准的基因列表进行整合。本研究所得结果涵盖超过17000种疾病、4000个ICD编码，以及超过11000组基因-疾病-编码组合。数据库访问网址：https://promis.rutgers.edu/pas/

搜集汇总

背景与挑战

背景概述

PAS是一个基因-疾病-代码注释数据库，集成了ICD-9和ICD-10代码，并与美国医学遗传学与基因组学学院批准的基因列表关联。它包含超过17,000种疾病、4,000个ICD代码和11,000个组合，支持在线搜索和导出功能。