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KSHV Requires vCyc to Overcome Replicative Senescence in Primary Human Lymphatic Endothelial Cells

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干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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We performed high throughput RNA-sequencing on KSHV-infected blood and lymphatic HMVECs at 48hpi as well as WTKSHV- or KSHVDvcyc-infected lymphatic HMVECS at 1wpi to identify differences in gene expression induced by KSHV in these two cell types and gene expression changes that require the KSHV latent gene vcyclin.

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2022-02-20
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