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2012-01-19
相关数据集
RNAseqencing of wild type (WT) and Ripk3-/- (KO) AML-12 cells in the presence (PA) of absence (C) of 125 µM palmitate-bovine serum albumin for 24 h
Purpose: Necroptosis as been implicated in various deseases. The goal of this study is to invastigate the impact of RIPK3 in the lipid metabolism of hepatic cells. Methods: AML-12 cells invalidated or
NIAID Data Ecosystem70
Functional Implications of Novel Human Acid Sphingomyelinase Splice Variants
BackgroundAcid sphingomyelinase (ASM) hydrolyses sphingomyelin and generates the lipid messenger ceramide, which mediates a variety of stress-related cellular processes. The pathological effects of dy
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Lipid droplet proteomics of THP1 macrophages infected with Mycobacterium tuberculosis
Growing evidence suggests the importance of lipid metabolism in pathogenesis of tuberculosis. Neutral lipids form the majority of lipids in caseous granulomas characteristic of tuberculosis. Macrophag
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Quantitative Lipid Droplet Proteome Analysis Identifies Annexin A3 as a Cofactor for HCV Particle Production
Cytosolic lipid droplets (LDs) are vital to Hepatitis C Virus (HCV) infection as the putative sites of virion assembly. To identify novel regulators of HCV particle production, we performed quantitati
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Growth Differentiation Factor 11 exacerbates non-alcoholic fatty liver disease in vitro and in vivo
Growth differentiation factor 11 (GDF11), also known as bone morphogenetic protein 11 (BMP11) is a member of the Growth differentiation factors (GDFs), a subfamily of proteins belonging to the transfo
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