Genome-wide mapping of meiotic double-strand breaks by sequencing Spo11 oligos.

The nonrandom distribution of meiotic recombination shapes patterns of inheritance and genome evolution, but chromosomal features governing this distribution are poorly understood减数分裂重组（meiotic recombination）的非随机分布塑造了遗传模式与基因组进化的格局，但目前学界对调控该分布的染色体特征仍知之甚少。