Characterisation data of common pharmaceutical excipient powders and tablets

Excipients are essential components within pharmaceutical formulations that are used to enhance properties such as the binding, disintegration, preservation, and patient friendliness of common dosage forms such as tablets, capsules, and inhalers. Common excipients such as micro-crystalline cellulose (MCC), dibasic calcium phosphate dihydrate (DCPD), and partially pre-gelatinised corn starch (PGS) therefore play a critical role in the design and production process of both new and old drug formulations. However, despite the importance of these powders, reference data is not publicly available. This is an extensive data set on MCC, DCPD, and PGS. This data set includes highly detailed information on individual grains, including particle sizes, crushing, and geometries. Using a compaction simulator, the powders and various mixtures thereof were compressed to make tablets, which were later subjected to a wide range of mechanical tests. This data set provides a reference point for the pharmaceutical industry, educators, and process developers alike.