miRNA expression profiling of ALL samples. Homo sapiens

We performed a comprehensive genome-wide miRNA expression profiling (MEP) of adult ALL samples with known genetic and clinical characteristics (n=65) in comparison with normal, non-malignant samples, with the objective of understanding the pathogenetic role of miRNA deregulation in ALL. Overall design: Total RNA, including miRNA, were extracted using Trizol and profiled using Agilent human miRNA V2.