Effects of hnRNPD and hnRNPU silencing on gene expression in SH-SY5Y cells. SH-SY5Y cells were treated with siRNA anti-hnRNPD (n=3), or anti-hnRNPU (n=3), or anti-Luciferase (n=3)
Dentatorubral-pallidoluysian Atrophy (DRPLA) is a human polyQ disease caused by the expansion of a CAG strech in the atrophin-1 (at-1) gene. In all vertebrates, a second atrophin gene (at-2) is presen
Selective neuronal vulnerability is a common, yet poorly understood characteristic of neurodegenerative diseases and is particularly prominent in Huntington's disease (HD). To determine how presence o
