Memory-like CD8 T-cells sustain the immune response to chronic viral infections.
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Memory-like CD8 T-cells sustain the immune response to chronic viral infections.
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创建时间：
2016-08-22
相关数据集
Characteristics and anatomic location of PD-1+TCF1+ stem-like CD8 T cells in chronic viral infection and cancer. Characteristics and anatomic location of PD-1+TCF1+ stem-like CD8 T cells in chronic viral infection and cancer
CD8 T cells play an essential role in anti-tumor immunity and chronic viral infections. Recent findings have delineated the differentiation pathway of CD8 T cells in accordance with the progenitor-pro
NIAID Data Ecosystem100
Tox reinforces the phenotype and longevity of dysfunctional T cell populations during chronic viral infection [KO vs WT Day 8]. Tox reinforces the phenotype and longevity of dysfunctional T cell populations during chronic viral infection [KO vs WT Day 8]
Chronic CD8 T-cell stimulation in persisting infections or tumors can induce a stable gene expression program, known as T-cell dysfunction or exhaustion, that limits the cell’s effector functions and
NIAID Data Ecosystem80
Early emergence of T central memory precursors programs clonal dominance during chronic viral infection [scRNAseq]
Chronic infection with cytomegalovirus (CMV) leads to long-term maintenance of extraordinarily large CMV-specific T cell populations. The magnitude of this so-called 'memory inflation' is thought to b
NIAID Data Ecosystem70
Memory-like HCV-specific CD8+ T cells retain a molecular scar after cure of chronic HCV infection. Memory-like HCV-specific CD8+ T cells retain a molecular scar after cure of chronic HCV infection
Investigation of phenotypical changes between exhausted HCV-specific CD8+ T cells during chronic infection and after DAA-mediated cure investigation of heterogeneity withhin the HCV-specific CD8+ T ce
NIAID Data Ecosystem80
Number of NS3-peptides that induce IFNγ production by CD4 T-cells or IL-2/IFNγ dual cytokine production by CD8 T-cells.
PRE, pre challenge. POST, post challenge.
NIAID Data Ecosystem70
