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Protein acylation regulates natural product biosynthesis

Name: Protein acylation regulates natural product biosynthesis
Creator: State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences
Published: 2018-04-14T10:03:02+08:00

integrated proteome resources2026-02-07 收录

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天然产物生物合成

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Protein acylation regulates natural product biosynthesis

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提供机构：

State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences

创建时间：

2018-04-14

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植物病原体功能基因组学

Lysine 2-hydroxyisobutyrylation , a recently discovered post-translational modification, plays a key role in the regulation of diverse cellular processes. Botrytis cinerea is a destructive necrotrophi

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Serine ADP-ribosylation depends on HPF1

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We report that serine ADPr is strictly dependent on HPF1 (histone PARylation factor 1. Quantitative proteomics revealed that serine ADPr does not occur in cells lacking HPF1. We identified three endog

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Table_11_Folate-deficiency induced acyl-CoA synthetase short-chain family member 2 increases lysine crotonylome involved in neural tube defects.XLSX

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Maternal folate deficiency increases the risk of neural tube defects (NTDs), but the mechanism remains unclear. Here, we established a mouse model of NTDs via low folate diets combined with MTX-induce

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Salinispora mooreana strain:DSM 45549 Genome sequencing and assembly. Salinispora mooreana strain:DSM 45549

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We believe this sequencing project will lead to the discovery of new biosynthetic enzymes that can be used to perform unique biochemical reactions that have broad applicability to the chemical industr

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Table_6_Global landscape of 2-hydroxyisobutyrylation in human pancreatic cancer.xlsx

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As a new type of post-translational modification (PTM), lysine 2-hydroxyisobutyrylation (Khib) was firstly identified in histones and functioned as a regulator of transactivation in mammals. However,

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Protein acylation regulates natural product biosynthesis

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