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ATF4 governs functional expansion of hematopoietic stem cells partially via Angptl3 in the fetal liver microenvironment

NIAID Data Ecosystem2026-03-08 收录

干细胞发育

肝脏微环境

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA276678 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2015-02-27

母体微生物组

干细胞发育

The maternal-microbiome influences child health. However, its impact on offspring’s stem cells, which regulate development, remains poorly understood.

Figshare2024-03-18 更新40

An interactive resource of molecular signalling in the developing human haematopoietic stem cell (HSC) niche [scRNA-seq]

干细胞发育

单细胞转录组学

The emergence of definitive human haematopoietic stem cells (HSCs) during Carnegie Stages (CS) 14-17 in the aorta-gonad-mesonephros (AGM) region is a complex and tightly regulated process. In a previo

NIAID Data Ecosystem30

Whole-transcriptome analysis of endothelial-to-hematopoietic stem cell transition

干细胞发育

内皮-造血转化转录组

Hematopoietic stem cells (HSCs) are generated via a natural transdifferentiation process known as endothelial-to-hematopoietic cell transition (EHT). Due to small numbers of embryonal arterial cells u

Alliance of Genome Resources10

Zscan4 mediates ubiquitination and degradation of co-repressor complex to promote chromatin accessibility in two-cell embryos and ESCs

表观遗传调控

干细胞发育

Zscan4 regulates chromatin accessibility and 2C in early embryos or 2C-like state in ESC cultures. Overall design: 2 repeats of Control and 2 repeats Zscan4 overexpression mouse ESCs.

NIAID Data Ecosystem40

Bulk RNA-Sequencing: Lineage-tracing hematopoietic stem cell origins in vivo to efficiently make human HLF+ HOXA+ hematopoietic progenitors from pluripotent stem cells

干细胞发育

干细胞定向分化

The developmental origin of blood-forming hematopoietic stem cells (HSCs) is a longstanding question. Here our non-invasive genetic lineage-tracing in mouse embryos pinpoints that artery endothelial c

NIAID Data Ecosystem20

ATF4 governs functional expansion of hematopoietic stem cells partially via Angptl3 in the fetal liver microenvironment

资源简介：

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