ERG controls B-cell development by promoting Igh V-to-DJ recombination
收藏NIAID Data Ecosystem2026-03-11 收录
官方服务:
资源简介:
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
应用场景:
创建时间:
2020-02-23
相关数据集
PHRF1 promotes the class switch recombination of IgA in CH12F3-2A cells-Dataset
 PHRF1 is an E3 ligase that promotes TGF-B signaling by ubiquitinating a homeodomain repressor TG-interacting factor (TGIF). The suppression of PHRF1 activity by PML-RAR facilitates the progression
DataONE2023-09-27 更新100
IGH analysis in pro-B cells with H3K4me3, H3K4me2, H3K9ac, H3K27me3, Pax5 and CTCF [ChIP-Seq]. Mus musculus
VH-DJH recombination of the immunoglobulin heavy-chain (Igh) locus is temporally and spatially controlled during early B-cell development, and yet no regulatory elements other than the VH gene promote
NIAID Data Ecosystem60
Altered 3D chromatin structure permits inversional recombination at the IgH locus
Immunoglobulin heavy chain (IgH) genes are assembled by two sequential DNA rearrangement events that are initiated by recombinase activating gene products (RAG) 1 and 2. Diversity gene segments (DH)
DataONE2021-08-26 更新30
Distinct mucosal or systemic microbiota exposures shape the functional B cell repertoire. Mus musculus strain:C57BL/6
Microbiota colonization causes profound B cell stimulation and immunoglobulin induction, yet mammals colonized with many taxa have highly complex individualized immunoglobulin repertoires. To deconstr
NIAID Data Ecosystem60
An enhancer in the middle of the Igκ locus orchestrates nuclear architecture to generate a diverse antigen receptor repertoire. An enhancer in the middle of the Igκ locus orchestrates nuclear architecture to generate a diverse antigen receptor repertoire
Purpose:The goal of this study is to assess transcriptome profile in the absence of a potent enhancer located in the V gene region of the Igκ locus in cell lines and mice Methods: RNAseq from CD19+ ce
NIAID Data Ecosystem50



