In this study, we examined the fitness landscape of a dynamic RNA structure using deep mutational scanning (DMS) experiments. Using a derivative of the group I intron from Tetrahymena thermophila, we
The table lists the HIV protein, the PUBMED ID presenting the directed mutation, motif pattern, hub symbol, the start and end of the motif and the mutation phenotype.
HIV-1 protease (PR) is a viral enzyme vital to the production of infectious virions. It is initially synthesized as part of the Gag-Pol polyprotein precursor in the infected cell. The free mature PR i