IRAK4 IN COMPLEX WITH inhibitor
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IRAK4 IN COMPLEX WITH inhibitor Descriptor: 4-(1-methylcyclopropyl)oxy-~{N}-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-6-(1-methylpyrazol-4-yl)pyrido[3,2-d]pyrimidin-2-amine, Interleukin-1 receptor-associated kinase 4 Authors: Xue, Y, Aagaard, A, Degorce, S.L. Deposit date: 2019-11-22 Release date: 2020-10-28 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.52 Å) Cite: Improving metabolic stability and removing aldehyde oxidase liability in a 5-azaquinazoline series of IRAK4 inhibitors. Bioorg.Med.Chem., 28, 2020
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2019-11-22
