Transcriptional effects of the myeloid cell-derived growth factor Oncomodulin on human monocytes and ipSC-derived sensory neurons. Transcriptional effects of the myeloid cell-derived growth factor Oncomodulin on human monocytes and ipSC-derived sensory neurons

To evaluate the possible translational relevance of oncomodulin (Ocm) and its receptor, we investigated the effect of Ocm on human peripheral blood monocytes and human induced pluripotent stem cells (iPSCs) derived sensory neurons Overall design: we performed gene expression profiling analysis using data obtained from RNA-seq of 2 different cells treated with control vehicle, forskolin, mannose and/or oncomodulin