Cisplatin is a potent chemotherapeutic drug, widely used in the treatment of various solid cancers. However, its clinical effectiveness is strongly limited by frequent severe adverse effects, such as
The spotty cattle models S8, S16 and S64 had a white surface with 8, 16 and 64 brown spots, respectively. BM: brown cattle model, WM: white cattle model, B: brown surface region, W: white surface regi