TRIM21 PRYSPRY bound to compound 209
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TRIM21 PRYSPRY bound to compound 209 Descriptor: (2~{S},4~{S})-1-[(3~{S})-3-azanyl-3-[2-[2-(2-hydroxyethyloxy)ethoxy]phenyl]propanoyl]-4-cyclohexyl-~{N}-[(2~{S})-1-(methylamino)-1-oxidanylidene-3-pyridin-4-yl-propan-2-yl]pyrrolidine-2-carboxamide, E3 ubiquitin-protein ligase TRIM21 Authors: Luptak, J. Deposit date: 2025-02-26 Release date: 2025-10-08 Last modified: 2026-04-22 Method: X-RAY DIFFRACTION (2.331 Å) Cite: State-selective small molecule degraders that preferentially remove aggregates and oligomers. Nat Commun, 16, 2025
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2025-02-26
