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Detection of sperm allelic ratio distortion by WGS

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NIAID Data Ecosystem2026-03-11 收录
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We sequenced the genomes of 3 boars using both their blood (diploid) and sperm (haploid) to identify allelic ratio distortion (ARD; a departure of the expected Mendelian allelic ratio of 05 : 0.5) in the haploid cells, which would indicate differences on the allelic performance on the haploid phases of spermatogenesis. This sperm ARD could contribute a portion of the Transmission Ratio Distortion observed on the allelic transmission from parents to offspring.

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2019-11-08
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