Mice deficient for Hdac3 in mesenchymal progenitor cell (under the PRX1 promoter) die perinataly and exhibit severly short limbs. Here we analyzed the differentiational gene expression in the limbs of
To elucidate the mechanisms involved in the acquisition of a fully differentiated beta-cell phenotype, we compared by microarray the mRNAs and the long non-coding RNAs expressed in newborn and adult r
The endocardium plays a pivotal role in governing myocardial development, and understanding the intrinsic regulatory insights will help apprehend pathological cardiomyopathy. Glycerol-3-phosphate acyl
Primary cilia are nearly ubiquitous, cellular projections that function to transduce molecular signals during development. Loss of functional primary cilia has a particularly profound effect on the de
Thyroid hormone (TH) is critical to normal brain development, but the mechanisms operating in this process are poorly understood. We used chromatin immunoprecipitation to enrich regions of DNA bound t