Native electrospray ionization mass spectrometry (ESI-MS) has emerged as a potent tool for examining the native-like structures of macromolecular complexes. Despite its utility, the predominant “buffe
CUMULATIVE SITE-DIRECTED CHARGE-CHANGE REPLACEMENTS IN BACTERIOPHAGE T4 LYSOZYME SUGGEST THAT LONG-RANGE ELECTROSTATIC INTERACTIONS CONTRIBUTE LITTLE TO PROTEIN STABILITY Descriptor: T4 LYSOZYME Autho
Detailed mutational analysis of the antibody interface (epitope and paratope). Change in stability and affinity predicted using FoldX, mCSM, ProAffiMuSeq, CUPSAT webservers/tools.
