Krox20 hindbrain regulation in Zebrafish [ATAC-seq]. Krox20 hindbrain regulation in Zebrafish [ATAC-seq]

In the present study, we have identified six enhancers located within the zebrafish krox20 locus, using accessibility data generated by ATAC-seq and characterized their activity profiles as well as their functions and interactions in the zebrafish hindbrain . We also investigated the orthologues in six evolutionary distant vertebrates of one of these element, showing a great variety of activity profiles demonstrating the striking evolutionary flexibility of this element . Overall design: Chromatin accessibility assessed by ATAC-seq from Zebrafish embryonic samples at different time points and anatomical positions.