Mature oocyte cytoplasm can reprogram somatic cell nuclei to the pluripotent state through a series of sequential events including protein exchange between the donor nucleus and ooplasm, chromatin rem
In urodele amphibians, limb regeneration involves the dedifferentiation of muscle myotubes into single cells that may acquire pluripotent potential. We have employed small molecules (myoseverin and BI
scRNA-seq time-series dataset of mouse embryonic fibroblast (MEF) reprogramming to induced pluripotent stem cells (iPSCs) subsetted to the serum condition and assayed using 10x Genomics. Contains 39 t
Suppression of P53 in conjunction with cell cycle arrest at G1 and appropriate extracellular environment markedly increases the efficiency in the transdifferentiation of human fibroblasts to iDA neuro
