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High Throughput Single-cell DNA Sequencing of Acute Myeloid Leukemia Tumors with Droplet Microfluidics

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NIAID Data Ecosystem2026-05-26 收录
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We developed a novel microfluidic platform to automatically barcode genomic DNA from individual cancer cells. Using this approach, we sequenced acute myeloid leukemia (AML) tumors targeting up to 62 loci relevant for the disease from thousands of cells. We predict that our platform will enable analysis of heterogeneity in AML and improve stratification and therapy selection.

创建时间:
2018-07-26
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