The refTSS is an annotated reference dataset for transcriptional start sites (TSS) in human and mouse. The dataset is generated by collecting, reprocessing and assembling various public resources.
During transcription initiation, RNA polymerase (RNAP) holoenzyme unwinds ~13 base pairs of promoter DNA, forming an RNAP-promoter open complex containing a single-stranded "transcription bubble," and
Despite almost 40 years of molecular genetics research in Escherichia coli a major fraction of its Transcription Start Sites (TSSs) are still unknown, limiting therefore our understanding of the regul
Understanding plant gene promoter architecture has long been a challenge due to the lack of relevant large-scale data sets and analysis methods. Here, we present a publicly available, large-scale tran
Additional file 6 List of primary transcription start sites (pTSS) identified for R. conorii transcripts expressed during the infection of tick vector (AAE2 + Rc) and human host (HMEC+Rc) cells, in vi
