PtdIns(4,5)P2 in cytokinesis pathway

Phosphatidylinositol 4,5-bisphosphate -- also known as PtdIns(4,5)P2 or PIP2 or PI(4,5)P2 -- acts as a central component in the process of bridge stability during the final steps of cytokinesis. Furthermore, PtdIns(4,5)P2 shows bidirectional interactions with many different metabolites such as anillin, ERM-complex. But also Septin2, F-actin and other depicted components visualized in the pathway are required to finalize cytokinesis between two sister cells.磷脂酰肌醇4,5-二磷酸，亦称PtdIns(4,5)P2、PIP2或PI(4,5)P2，作为细胞分裂末期细胞桥稳定性过程中的核心组分。此外，PtdIns(4,5)P2与多种代谢物如anillin、ERM复合体等表现出双向交互作用。然而，细胞分裂过程中，需最终完成姐妹细胞间细胞分裂的还有Septin2、F-actin以及其他在通路中呈现的描述性组分。