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Supplemental data for the thrombo JAK study
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Application of Sequential Palladium Catalysis for the Discovery of Janus Kinase Inhibitors in the Benzo[ c ]pyrrolo[2,3‑ h ][1,6]naphthyridin-5-one (BPN) Series
The present account describes the discovery and development of a new benzo[c]pyrrolo[2,3-h][1,6]naphthyridin-5-one (BPN) JAK inhibitory chemotype that has produced selective JAK inhibitors. Seque
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Figure 1: Dynamics of GPVI-Fc Binding and Platelet Adhesion to Collagen Under Flow
Glycoprotein VI–fragment crystallizable (GPVI-Fc) (50 μg/ml final concentration; 333 nM) labeled with phycoerythrin (PE)-conjugated anti–human-Fc antibody (red) was added to blood containing ab
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Supplementary Material for: Instant Reocclusion following Mechanical Thrombectomy of in situ Thromboocclusion and the Role of Low-Dose Intra-Arterial Tirofiban
Background: An in situ thromboocclusion (IST) is defined as an infarct extensively involving all or most of a stenosed arterial territory, which is one major stroke mechanism related to intracranial a
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The Prothrombotic Phenotypes in Familial Protein C Deficiency Are Differentiated by Computational Modeling of Thrombin Generation
The underlying cause of thrombosis in a large protein C (PC) deficient Vermont kindred appears to be multicausal and not explained by PC deficiency alone. We evaluated the contribution of coagulation
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Additional file 3 of Age- and sex-specific transcriptomic changes drive the prothrombotic potential of megakaryocytes
Supplementary Material 3.
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