Some of the significant disease-pathways associated with COVID-19.

NIAID Data Ecosystem2026-03-12 收录

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https://figshare.com/articles/dataset/Some_of_the_significant_disease-pathways_associated_with_COVID-19_/15076351 数据链接链接失效反馈

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(Drugs in Clinical-Drug group are highlighted in bold font).

创建时间：

2021-07-29

datasheet1_Discovery of Kasugamycin as a Potent Inhibitor of Glycoside Hydrolase Family 18 Chitinases.pdf

几丁质酶抑制剂

药物靶点发现

Kasugamycin, a well-known aminoglycoside antibiotic, has been used widely in agriculture and medicine to combat microbial pathogens by binding the ribosome to inhibit translation. Here, kasugamycin wa

NIAID Data Ecosystem30

Structural Determination of Functional Units of the Nucleotide Binding Domain (NBD94) of the Reticulocyte Binding Protein Py235 of Plasmodium yoelii

蛋白质结构

药物靶点发现

BackgroundInvasion of the red blood cells (RBC) by the merozoite of malaria parasites involves a large number of receptor ligand interactions. The reticulocyte binding protein homologue family (RH) pl

NIAID Data Ecosystem20

Data_Sheet_1_Interaction Mechanisms Between the NOX4/ROS and RhoA/ROCK1 Signaling Pathways as New Anti- fibrosis Targets of Ursolic Acid in Hepatic Stellate Cells.pdf

肝纤维化机制研究

药物靶点发现

BackgroundStudies have shown that both NOX4 and RhoA play essential roles in fibrosis and that they regulate each other. In lung fibrosis, NOX4/ROS is located upstream of the RhoA/ROCK1 signaling path

NIAID Data Ecosystem20

Identification of Druggable Cancer Driver Genes Amplified across TCGA Datasets

癌症驱动基因

药物靶点发现

The Cancer Genome Atlas (TCGA) projects have advanced our understanding of the driver mutations, genetic backgrounds, and key pathways activated across cancer types. Analysis of TCGA datasets have mos

NIAID Data Ecosystem30

Additional file 2: Figure S1. of A transcriptome-based protein network that identifies new therapeutic targets in colorectal cancer

癌细胞转录组

药物靶点发现

Hierarchical clustering of colorectal carcinoma (CRC) and normal colon tissue (NT) based on gene expression profiling obtained from each type of PCR array. Log2-transformed fold-change values from gen

NIAID Data Ecosystem20

Some of the significant disease-pathways associated with COVID-19.

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