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Genetic ablation of <i>Gba2</i> does not correct lysosomal defects.

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NIAID Data Ecosystem2026-03-08 收录
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Levels of GalCer, GlcCer, Cer, GlcSph and gangliosides (GM3 and GM2), and activity of lysosomal enzymes β-hexosaminidase in whole brain homogenates of mice resulting from the crossing of Gba2-/- mice with Npc1-/- mice. Data (n = 5–6 per group) were analyzed using the Kruskal-Wallis test with post hoc Dunn’s multiple comparison test. * P < 0.05, ** P < 0.01 and *** P < 0.001 from Npc1+/+/Gba2+/+ Genetic ablation of Gba2 does not correct lysosomal defects.

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2015-08-14
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